Cloning Vectors
Cosmids lack

cleavage site for the insertion of foreign DNA
origin of replication
genes coding for viral proteins
marker genes coding for replication

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Cloning Vectors
Charon vectors are different from EMBL vectors because

physical separation of lambda arm from central fragment is required
they have more extensive range of restriction targets with in their polylinkers.
physical separation of lambda arm from central fragment is not required
both (a) and (b)

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