Cell Signalling and Transduction
Why is it that inhaling nitric oxide reduces blood pressure only in the lung tissue and not elsewhere in the body*?

Because other body tissues use a different signaling molecule
None of these
Because nitric oxide breaks down quickly and thus cannot travel far
Because nitric oxide cannot cross cell membranes and enter the blood

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Cell Signalling and Transduction
If a disease of the blood vessels caused the endothelial cells of the vessel to die, what effect would that have on the cellular activities associated with vasodilation?

Smooth muscle cells could not be made to relax
All of these
Nitric oxide would no longer be produced
It would be more difficult to increase blood flow and reduce blood pressure

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Cell Signalling and Transduction
Nitroglycerin has long been administered to human patients suffering from chronic chest pain (angina). This medication works because it

breaks down into nitric oxide, which increases blood flow to the heart
is broken down into hormones that affect the heart
interferes with chemical cascades that trigger contraction of heart muscle
mimics the action of signal receptors

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Cell Signalling and Transduction
cAMP and cGMP are derived from

ATP and GTP by the actions of adenylate cyclase and guanylate cyclase respectively
ATP and GTP by the actions of guanylate cyclase and adenylate cyclase respectively
None of these
GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively

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Cell Signalling and Transduction
In terms of cell communication, what do bacterial pathogens such as cholera and anthrax have in common?

They alter the chemical structure of key signaling molecules
They destroy the receptors for key signaling molecules
They prevent the production of key signaling molecules
They block the normal functioning of signal transduction mechanisms

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Cell Signalling and Transduction
Which of the following is true about a hydrophilic signaling molecule?

It might trigger a signal cascade that causes some effect in a cell
Since it can enter the cell, it directly affects some specific cell process
It is a steroid
Its receptor is located in the cytosol of the target cell

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