Cell Signalling and Transduction
Why is it that inhaling nitric oxide reduces blood pressure only in the lung tissue and not elsewhere in the body*?

Because other body tissues use a different signaling molecule
Because nitric oxide breaks down quickly and thus cannot travel far
Because nitric oxide cannot cross cell membranes and enter the blood
None of these

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Cell Signalling and Transduction
Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it

allows hydrophilic signaling molecules to cross the plasma membrane
makes the receptor more likely to capture the signaling, molecule
None of these
changes the shape and thus the enzymatic activity of the proteins involved

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Cell Signalling and Transduction
If a disease of the blood vessels caused the endothelial cells of the vessel to die, what effect would that have on the cellular activities associated with vasodilation?

Smooth muscle cells could not be made to relax
It would be more difficult to increase blood flow and reduce blood pressure
All of these
Nitric oxide would no longer be produced

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Cell Signalling and Transduction
Which of the following is true about a hydrophilic signaling molecule?

It might trigger a signal cascade that causes some effect in a cell
It is a steroid
Its receptor is located in the cytosol of the target cell
Since it can enter the cell, it directly affects some specific cell process

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Cell Signalling and Transduction
cAMP and cGMP are derived from

GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively
None of these
ATP and GTP by the actions of adenylate cyclase and guanylate cyclase respectively
ATP and GTP by the actions of guanylate cyclase and adenylate cyclase respectively

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