Cell Signalling and Transduction
Two key organizing principles for large multicellular organisms are

prokaryotic cell structure and cell specialization
cell specialization and communication between cells
communication between cells and simple nerve reflexes
simple nerve reflexes and cell specialization

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Cell Signalling and Transduction
If a disease of the blood vessels caused the endothelial cells of the vessel to die, what effect would that have on the cellular activities associated with vasodilation?

It would be more difficult to increase blood flow and reduce blood pressure
Smooth muscle cells could not be made to relax
All of these
Nitric oxide would no longer be produced

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