Cell Signalling and Transduction
Nitroglycerin has long been administered to human patients suffering from chronic chest pain (angina). This medication works because it

breaks down into nitric oxide, which increases blood flow to the heart
is broken down into hormones that affect the heart
mimics the action of signal receptors
interferes with chemical cascades that trigger contraction of heart muscle

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Cell Signalling and Transduction
If a disease of the blood vessels caused the endothelial cells of the vessel to die, what effect would that have on the cellular activities associated with vasodilation?

Nitric oxide would no longer be produced
It would be more difficult to increase blood flow and reduce blood pressure
All of these
Smooth muscle cells could not be made to relax

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Cell Signalling and Transduction
cAMP and cGMP are derived from

ATP and GTP by the actions of guanylate cyclase and adenylate cyclase respectively
GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively
ATP and GTP by the actions of adenylate cyclase and guanylate cyclase respectively
None of these

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Cell Signalling and Transduction
Why is it that inhaling nitric oxide reduces blood pressure only in the lung tissue and not elsewhere in the body*?

Because other body tissues use a different signaling molecule
Because nitric oxide breaks down quickly and thus cannot travel far
None of these
Because nitric oxide cannot cross cell membranes and enter the blood

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