Cell Signalling and Transduction
The signaling molecules called steroid hormones

never enter the blood of humans
bind to cell surface receptors to trigger chemical cascades
are made in one location of the body but have their effects some distance away
are hydrophilic and so cannot penetrate the plasma membrane

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Cell Signalling and Transduction
If a disease of the blood vessels caused the endothelial cells of the vessel to die, what effect would that have on the cellular activities associated with vasodilation?

Smooth muscle cells could not be made to relax
All of these
Nitric oxide would no longer be produced
It would be more difficult to increase blood flow and reduce blood pressure

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