Cell Signalling and Transduction
The signaling molecules called steroid hormones

bind to cell surface receptors to trigger chemical cascades
are made in one location of the body but have their effects some distance away
are hydrophilic and so cannot penetrate the plasma membrane
never enter the blood of humans

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Cell Signalling and Transduction
When a __________ reaches its __________ , there is a specific means of receiving it and acting on the message. This task is the responsibility of specialized proteins called __________ .

signaling molecule; target cell; receptors
signaling molecule; receptor; G proteins
kinase; receptor; proteases
signaling molecule; target cell; G proteins

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Cell Signalling and Transduction
Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it

changes the shape and thus the enzymatic activity of the proteins involved
None of these
allows hydrophilic signaling molecules to cross the plasma membrane
makes the receptor more likely to capture the signaling, molecule

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Cell Signalling and Transduction
The binding of ligands to many G-proteins linked receptors leads to shortlived

decrease in the concentration of certain intracellular signaling molecules called second messenger
decrease in the concentration of certain extracellular signaling molecules called first messenger
increase in the concentration of certain intracellular signaling molecules called second messenger
increase in the concentration of certain extracellular signaling molecules called first messenger

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