Cell Signalling and Transduction
The signaling molecules called steroid hormones

bind to cell surface receptors to trigger chemical cascades
are made in one location of the body but have their effects some distance away
never enter the blood of humans
are hydrophilic and so cannot penetrate the plasma membrane

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Cell Signalling and Transduction
Nitroglycerin has long been administered to human patients suffering from chronic chest pain (angina). This medication works because it

is broken down into hormones that affect the heart
mimics the action of signal receptors
breaks down into nitric oxide, which increases blood flow to the heart
interferes with chemical cascades that trigger contraction of heart muscle

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