Cell Signalling and Transduction
cAMP and cGMP are derived from

ATP and GTP by the actions of guanylate cyclase and adenylate cyclase respectively
None of these
ATP and GTP by the actions of adenylate cyclase and guanylate cyclase respectively
GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively

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Cell Signalling and Transduction
Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it

changes the shape and thus the enzymatic activity of the proteins involved
makes the receptor more likely to capture the signaling, molecule
None of these
allows hydrophilic signaling molecules to cross the plasma membrane

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Cell Signalling and Transduction
The binding of ligands to many G-proteins linked receptors leads to shortlived

decrease in the concentration of certain extracellular signaling molecules called first messenger
increase in the concentration of certain extracellular signaling molecules called first messenger
decrease in the concentration of certain intracellular signaling molecules called second messenger
increase in the concentration of certain intracellular signaling molecules called second messenger

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Cell Signalling and Transduction
Nitroglycerin has long been administered to human patients suffering from chronic chest pain (angina). This medication works because it

breaks down into nitric oxide, which increases blood flow to the heart
interferes with chemical cascades that trigger contraction of heart muscle
is broken down into hormones that affect the heart
mimics the action of signal receptors

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Cell Signalling and Transduction
Which of the following is true about a hydrophilic signaling molecule?

It might trigger a signal cascade that causes some effect in a cell
Its receptor is located in the cytosol of the target cell
Since it can enter the cell, it directly affects some specific cell process
It is a steroid

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Cell Signalling and Transduction
Two key organizing principles for large multicellular organisms are

cell specialization and communication between cells
communication between cells and simple nerve reflexes
simple nerve reflexes and cell specialization
prokaryotic cell structure and cell specialization

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