Cell Signalling and Transduction
The binding of ligands to many G-proteins linked receptors leads to shortlived

increase in the concentration of certain intracellular signaling molecules called second messenger
decrease in the concentration of certain intracellular signaling molecules called second messenger
increase in the concentration of certain extracellular signaling molecules called first messenger
decrease in the concentration of certain extracellular signaling molecules called first messenger

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Cell Signalling and Transduction
Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it

allows hydrophilic signaling molecules to cross the plasma membrane
makes the receptor more likely to capture the signaling, molecule
changes the shape and thus the enzymatic activity of the proteins involved
None of these

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Cell Signalling and Transduction
The signaling molecules called steroid hormones

never enter the blood of humans
are made in one location of the body but have their effects some distance away
bind to cell surface receptors to trigger chemical cascades
are hydrophilic and so cannot penetrate the plasma membrane

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Cell Signalling and Transduction
Why is it that inhaling nitric oxide reduces blood pressure only in the lung tissue and not elsewhere in the body*?

None of these
Because nitric oxide cannot cross cell membranes and enter the blood
Because nitric oxide breaks down quickly and thus cannot travel far
Because other body tissues use a different signaling molecule

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