Cell Signalling and Transduction
The binding of ligands to many G-proteins linked receptors leads to shortlived

decrease in the concentration of certain extracellular signaling molecules called first messenger
increase in the concentration of certain extracellular signaling molecules called first messenger
decrease in the concentration of certain intracellular signaling molecules called second messenger
increase in the concentration of certain intracellular signaling molecules called second messenger

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Cell Signalling and Transduction
A signal cascade induced by adrenaline or thyroxine

involves the activation of a G protein
must begin with receipt of the signal molecule by a surface receptor
results in the activation of a sequence of enzymes needed for the cell effect
All of these

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Cell Signalling and Transduction
Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it

changes the shape and thus the enzymatic activity of the proteins involved
makes the receptor more likely to capture the signaling, molecule
allows hydrophilic signaling molecules to cross the plasma membrane
None of these

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Cell Signalling and Transduction
Nitroglycerin has long been administered to human patients suffering from chronic chest pain (angina). This medication works because it

breaks down into nitric oxide, which increases blood flow to the heart
mimics the action of signal receptors
is broken down into hormones that affect the heart
interferes with chemical cascades that trigger contraction of heart muscle

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