Cell Signalling and Transduction
Nitroglycerin has long been administered to human patients suffering from chronic chest pain (angina). This medication works because it

breaks down into nitric oxide, which increases blood flow to the heart
is broken down into hormones that affect the heart
interferes with chemical cascades that trigger contraction of heart muscle
mimics the action of signal receptors

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Cell Signalling and Transduction
If a disease of the blood vessels caused the endothelial cells of the vessel to die, what effect would that have on the cellular activities associated with vasodilation?

Nitric oxide would no longer be produced
All of these
It would be more difficult to increase blood flow and reduce blood pressure
Smooth muscle cells could not be made to relax

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