Cell Signalling and Transduction
In the signal transduction mechanism known as protein phosphorylation

receptor kinases play a key role in triggering the signal cascade
All of these
the signaling molecule binds to a surface receptor
phosphorylated proteins act with enzymes to trigger the signal cascade

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Cell Signalling and Transduction
A signal cascade induced by adrenaline or thyroxine

results in the activation of a sequence of enzymes needed for the cell effect
involves the activation of a G protein
must begin with receipt of the signal molecule by a surface receptor
All of these

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Cell Signalling and Transduction
The binding of ligands to many G-proteins linked receptors leads to shortlived

increase in the concentration of certain intracellular signaling molecules called second messenger
increase in the concentration of certain extracellular signaling molecules called first messenger
decrease in the concentration of certain extracellular signaling molecules called first messenger
decrease in the concentration of certain intracellular signaling molecules called second messenger

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Cell Signalling and Transduction
Nitroglycerin has long been administered to human patients suffering from chronic chest pain (angina). This medication works because it

mimics the action of signal receptors
breaks down into nitric oxide, which increases blood flow to the heart
interferes with chemical cascades that trigger contraction of heart muscle
is broken down into hormones that affect the heart

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