Cell Signalling and Transduction
The enzyme that catalyzes the splitting of PIP2 into two molecules of inositol triphosphate (IP3) and diacylglycerol in cell signaling, is

lipokinase
phospholipase C
phosphokinase C
phosphodiesterase C

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Cell Signalling and Transduction
Why is it that inhaling nitric oxide reduces blood pressure only in the lung tissue and not elsewhere in the body*?

Because nitric oxide breaks down quickly and thus cannot travel far
Because nitric oxide cannot cross cell membranes and enter the blood
None of these
Because other body tissues use a different signaling molecule

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Cell Signalling and Transduction
If a disease of the blood vessels caused the endothelial cells of the vessel to die, what effect would that have on the cellular activities associated with vasodilation?

Nitric oxide would no longer be produced
It would be more difficult to increase blood flow and reduce blood pressure
All of these
Smooth muscle cells could not be made to relax

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Cell Signalling and Transduction
Nitroglycerin has long been administered to human patients suffering from chronic chest pain (angina). This medication works because it

breaks down into nitric oxide, which increases blood flow to the heart
interferes with chemical cascades that trigger contraction of heart muscle
is broken down into hormones that affect the heart
mimics the action of signal receptors

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Cell Signalling and Transduction
The signaling molecules called steroid hormones

are made in one location of the body but have their effects some distance away
bind to cell surface receptors to trigger chemical cascades
are hydrophilic and so cannot penetrate the plasma membrane
never enter the blood of humans

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