Cell Signalling and Transduction
The enzyme that catalyzes the splitting of PIP2 into two molecules of inositol triphosphate (IP3) and diacylglycerol in cell signaling, is

phosphokinase C
phospholipase C
phosphodiesterase C
lipokinase

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Cell Signalling and Transduction
The binding of ligands to many G-proteins linked receptors leads to shortlived

decrease in the concentration of certain intracellular signaling molecules called second messenger
increase in the concentration of certain intracellular signaling molecules called second messenger
decrease in the concentration of certain extracellular signaling molecules called first messenger
increase in the concentration of certain extracellular signaling molecules called first messenger

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Cell Signalling and Transduction
cAMP and cGMP are derived from

ATP and GTP by the actions of adenylate cyclase and guanylate cyclase respectively
None of these
GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively
ATP and GTP by the actions of guanylate cyclase and adenylate cyclase respectively

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Cell Signalling and Transduction
In terms of cell communication, what do bacterial pathogens such as cholera and anthrax have in common?

They alter the chemical structure of key signaling molecules
They block the normal functioning of signal transduction mechanisms
They destroy the receptors for key signaling molecules
They prevent the production of key signaling molecules

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Cell Signalling and Transduction
Nitroglycerin has long been administered to human patients suffering from chronic chest pain (angina). This medication works because it

interferes with chemical cascades that trigger contraction of heart muscle
mimics the action of signal receptors
is broken down into hormones that affect the heart
breaks down into nitric oxide, which increases blood flow to the heart

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Cell Signalling and Transduction
Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it

allows hydrophilic signaling molecules to cross the plasma membrane
makes the receptor more likely to capture the signaling, molecule
changes the shape and thus the enzymatic activity of the proteins involved
None of these

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