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Cell Signalling and Transduction

Cell Signalling and Transduction
SH2 domains specifically bind to

phosphorylated serine residues
GDP
phosphorylated tyrosine residues
Ca2+

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Cell Signalling and Transduction
In paracrine signaling, the signaling molecules affects only

target cells close to the cell from which it was secreted
target cells distant from its site of synthesis in cells of an endocrine organ
None of these
both (a) and (b)

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Cell Signalling and Transduction
What is the name of the protein signaling molecule that alters glucose uptake, and where would its receptors be located?

Insulin; many different cell types that use glucose for fuel
NGF; the nerves involved in simple reflexes
Insulin; beta cells of the pancreas
PDGF; the blood

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Cell Signalling and Transduction
The hormone or ligand can be considered as

second messenger
first messenger
none of these
both (a) and (b)

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Cell Signalling and Transduction
The enzyme that catalyzes the splitting of PIP2 into two molecules of inositol triphosphate (IP3) and diacylglycerol in cell signaling, is

lipokinase
phosphokinase C
phospholipase C
phosphodiesterase C

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Cell Signalling and Transduction
In vasodilation, proper nerve signals sent to blood vessels cause

reduced blood pressure
relaxation of smooth muscle cells
All of these
the release of nitric oxide from endothelial cells

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