Cell Signalling and Transduction
The signaling molecules called steroid hormones

are made in one location of the body but have their effects some distance away
bind to cell surface receptors to trigger chemical cascades
are hydrophilic and so cannot penetrate the plasma membrane
never enter the blood of humans

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Cell Signalling and Transduction
Nitroglycerin has long been administered to human patients suffering from chronic chest pain (angina). This medication works because it

mimics the action of signal receptors
is broken down into hormones that affect the heart
interferes with chemical cascades that trigger contraction of heart muscle
breaks down into nitric oxide, which increases blood flow to the heart

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