Cell Signalling and Transduction
The binding of ligands to many G-proteins linked receptors leads to shortlived

increase in the concentration of certain extracellular signaling molecules called first messenger
decrease in the concentration of certain extracellular signaling molecules called first messenger
decrease in the concentration of certain intracellular signaling molecules called second messenger
increase in the concentration of certain intracellular signaling molecules called second messenger

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Cell Signalling and Transduction
Two key organizing principles for large multicellular organisms are

prokaryotic cell structure and cell specialization
cell specialization and communication between cells
simple nerve reflexes and cell specialization
communication between cells and simple nerve reflexes

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