Cell Signalling and Transduction
If a disease of the blood vessels caused the endothelial cells of the vessel to die, what effect would that have on the cellular activities associated with vasodilation?

It would be more difficult to increase blood flow and reduce blood pressure
Nitric oxide would no longer be produced
All of these
Smooth muscle cells could not be made to relax

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Cell Signalling and Transduction
The binding of ligands to many G-proteins linked receptors leads to shortlived

increase in the concentration of certain extracellular signaling molecules called first messenger
decrease in the concentration of certain intracellular signaling molecules called second messenger
decrease in the concentration of certain extracellular signaling molecules called first messenger
increase in the concentration of certain intracellular signaling molecules called second messenger

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Cell Signalling and Transduction
The signaling molecules called steroid hormones

are made in one location of the body but have their effects some distance away
never enter the blood of humans
are hydrophilic and so cannot penetrate the plasma membrane
bind to cell surface receptors to trigger chemical cascades

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Cell Signalling and Transduction
When a __________ reaches its __________ , there is a specific means of receiving it and acting on the message. This task is the responsibility of specialized proteins called __________ .

signaling molecule; target cell; receptors
signaling molecule; target cell; G proteins
kinase; receptor; proteases
signaling molecule; receptor; G proteins

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Cell Signalling and Transduction
Why is it that inhaling nitric oxide reduces blood pressure only in the lung tissue and not elsewhere in the body*?

None of these
Because other body tissues use a different signaling molecule
Because nitric oxide breaks down quickly and thus cannot travel far
Because nitric oxide cannot cross cell membranes and enter the blood

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