Cell Signalling and Transduction
When a __________ reaches its __________ , there is a specific means of receiving it and acting on the message. This task is the responsibility of specialized proteins called __________ .

signaling molecule; target cell; G proteins
signaling molecule; receptor; G proteins
kinase; receptor; proteases
signaling molecule; target cell; receptors

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Cell Signalling and Transduction
The signaling molecules called steroid hormones

bind to cell surface receptors to trigger chemical cascades
are made in one location of the body but have their effects some distance away
are hydrophilic and so cannot penetrate the plasma membrane
never enter the blood of humans

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Cell Signalling and Transduction
The binding of ligands to many G-proteins linked receptors leads to shortlived

increase in the concentration of certain extracellular signaling molecules called first messenger
increase in the concentration of certain intracellular signaling molecules called second messenger
decrease in the concentration of certain intracellular signaling molecules called second messenger
decrease in the concentration of certain extracellular signaling molecules called first messenger

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Cell Signalling and Transduction
Which of the following is true about a hydrophilic signaling molecule?

It is a steroid
It might trigger a signal cascade that causes some effect in a cell
Since it can enter the cell, it directly affects some specific cell process
Its receptor is located in the cytosol of the target cell

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