Cell Signalling and Transduction
Two key organizing principles for large multicellular organisms are

prokaryotic cell structure and cell specialization
communication between cells and simple nerve reflexes
cell specialization and communication between cells
simple nerve reflexes and cell specialization

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Cell Signalling and Transduction
In the signal transduction mechanism known as protein phosphorylation

the signaling molecule binds to a surface receptor
receptor kinases play a key role in triggering the signal cascade
phosphorylated proteins act with enzymes to trigger the signal cascade
All of these

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