Cell Signalling and Transduction
Which of the following is true about a hydrophilic signaling molecule?

It is a steroid
Since it can enter the cell, it directly affects some specific cell process
Its receptor is located in the cytosol of the target cell
It might trigger a signal cascade that causes some effect in a cell

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Cell Signalling and Transduction
The signaling molecules called steroid hormones

never enter the blood of humans
are made in one location of the body but have their effects some distance away
are hydrophilic and so cannot penetrate the plasma membrane
bind to cell surface receptors to trigger chemical cascades

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Cell Signalling and Transduction
Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it

makes the receptor more likely to capture the signaling, molecule
None of these
changes the shape and thus the enzymatic activity of the proteins involved
allows hydrophilic signaling molecules to cross the plasma membrane

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