Cell Signalling and Transduction
Which of the following is true about a hydrophilic signaling molecule?

Its receptor is located in the cytosol of the target cell
It might trigger a signal cascade that causes some effect in a cell
Since it can enter the cell, it directly affects some specific cell process
It is a steroid

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Cell Signalling and Transduction
If a disease of the blood vessels caused the endothelial cells of the vessel to die, what effect would that have on the cellular activities associated with vasodilation?

Smooth muscle cells could not be made to relax
Nitric oxide would no longer be produced
It would be more difficult to increase blood flow and reduce blood pressure
All of these

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Cell Signalling and Transduction
cAMP and cGMP are derived from

ATP and GTP by the actions of guanylate cyclase and adenylate cyclase respectively
ATP and GTP by the actions of adenylate cyclase and guanylate cyclase respectively
GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively
None of these

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Cell Signalling and Transduction
In the signal transduction mechanism known as protein phosphorylation

phosphorylated proteins act with enzymes to trigger the signal cascade
All of these
receptor kinases play a key role in triggering the signal cascade
the signaling molecule binds to a surface receptor

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Cell Signalling and Transduction
Why is it that inhaling nitric oxide reduces blood pressure only in the lung tissue and not elsewhere in the body*?

Because other body tissues use a different signaling molecule
Because nitric oxide cannot cross cell membranes and enter the blood
Because nitric oxide breaks down quickly and thus cannot travel far
None of these

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