Cell Signalling and Transduction
Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it

allows hydrophilic signaling molecules to cross the plasma membrane
changes the shape and thus the enzymatic activity of the proteins involved
None of these
makes the receptor more likely to capture the signaling, molecule

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Cell Signalling and Transduction
A signal cascade induced by adrenaline or thyroxine

All of these
must begin with receipt of the signal molecule by a surface receptor
results in the activation of a sequence of enzymes needed for the cell effect
involves the activation of a G protein

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