Microorganisms and Disease
Which of the following statements is not true regarding Mycobacterium tuberculosis and/or the disease it causes?

The pathogen can live inside macrophages
None of these
Antibodies to the pathogen are protective
The pathogen contains mycolic acid in its cell wall

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Microorganisms and Disease
A major difference between EHEC and EPEC is

EHEC secretes a Shiga-like toxin and EPEC does not
EHEC possesses a type III secretion system and EPEC does not
EPEC rearranges host cell actin and EHEC does not
EPEC passes through the placenta to infect the fetus and EHEC does not

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Microorganisms and Disease
Cholera toxin is an A-B type toxin in which the B portions bind to a receptor on a host cell and the A portion enters the cell to cause

ADP ribosylation of adenylate cyclase that stops production of cAMP
ADP ribosylation of guanylate cyclase that stimulates production of cGMP
ADP ribosylation of a G protein that locks it into an active form that stimulates adenylate cyclase to make cAMP
cleavage of rRNA that results in disruption of ribosome function

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Microorganisms and Disease
Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine?

The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings
A limited number of capsule types
The possession of a segmented RNA genome
The ability of the Rotavirus to be transmitted faster

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

cause ADP ribosylation of a factor involved in protein synthesis
forms cAMP that leads to fluid accumulation
binds host cell receptors found on heart cells
lysis macrophages with the release of cytokines

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