Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

Both organisms cause skin and respiratory tract infections
Both organisms are gram-positive spore formers
Diphtheria toxin and edema toxin are ADP ribosylating toxins
The most serious disease symptoms are the direct result of toxin action

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Microorganisms and Disease
Which of the following is true regarding anthrax?

Anthrax is caused by a virus
Inhalation Anthrax requires infection with a large number of spores
Inhalation anthrax and cutaneous anthrax are caused by separate strains of Bacillus anthracis
Anthrax is highly contagious

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Microorganisms and Disease
Type III secretion systems are used to inject "effector" proteins directly into a host cell. Salmonella uses a type III secretion system to help the pathogen to

survive within macrophages
survive the acid pH of the stomach
secrete LT (heat labile toxin) and ST (heat stable toxin) into the lumen of the intestine
activate T cells to proliferate and secrete cytokines

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Microorganisms and Disease
A major difference between EHEC and EPEC is

EPEC passes through the placenta to infect the fetus and EHEC does not
EPEC rearranges host cell actin and EHEC does not
EHEC possesses a type III secretion system and EPEC does not
EHEC secretes a Shiga-like toxin and EPEC does not

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