Microorganisms and Disease
A major difference between EHEC and EPEC is

EPEC rearranges host cell actin and EHEC does not
EHEC possesses a type III secretion system and EPEC does not
EHEC secretes a Shiga-like toxin and EPEC does not
EPEC passes through the placenta to infect the fetus and EHEC does not

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Microorganisms and Disease
Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine?

The ability of the Rotavirus to be transmitted faster
The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings
A limited number of capsule types
The possession of a segmented RNA genome

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Microorganisms and Disease
Type III secretion systems are used to inject "effector" proteins directly into a host cell. Salmonella uses a type III secretion system to help the pathogen to

survive within macrophages
survive the acid pH of the stomach
activate T cells to proliferate and secrete cytokines
secrete LT (heat labile toxin) and ST (heat stable toxin) into the lumen of the intestine

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Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

Both organisms are gram-positive spore formers
Both organisms cause skin and respiratory tract infections
Diphtheria toxin and edema toxin are ADP ribosylating toxins
The most serious disease symptoms are the direct result of toxin action

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