Microorganisms and Disease
Mucus helps in protecting against pathogens by

lowering the pH
facilitating the growth of normal flora
sequestering Iron
blocking access and attachment of pathogens to mucosal surfaces

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

cause ADP ribosylation of a factor involved in protein synthesis
forms cAMP that leads to fluid accumulation
lysis macrophages with the release of cytokines
binds host cell receptors found on heart cells

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