Microorganisms and Disease
The "A" subunit of diphtheria toxin

cause ADP ribosylation of a factor involved in protein synthesis
binds host cell receptors found on heart cells
lysis macrophages with the release of cytokines
forms cAMP that leads to fluid accumulation

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Microorganisms and Disease
Prontosil is

an effective antibacterial when used in animals
an effective antibacterial both in animals as well as in in-vitro cultures
not used as an antibacterial agent
an effective antibacterial when used in in-vitro cultures

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Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

Diphtheria toxin and edema toxin are ADP ribosylating toxins
Both organisms cause skin and respiratory tract infections
Both organisms are gram-positive spore formers
The most serious disease symptoms are the direct result of toxin action

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Microorganisms and Disease
Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine?

The possession of a segmented RNA genome
A limited number of capsule types
The ability of the Rotavirus to be transmitted faster
The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings

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Microorganisms and Disease
Plastic implants can pose a serious nosocomial infection problem because

All of these
phagocytes have trouble moving on the plastic surface
phagocytes have trouble engulfing bacteria embedded in a biofilm
infected implants usually have to be surgically removed

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