Microorganisms and Disease
Type III secretion systems are used to inject "effector" proteins directly into a host cell. Salmonella uses a type III secretion system to help the pathogen to

secrete LT (heat labile toxin) and ST (heat stable toxin) into the lumen of the intestine
survive the acid pH of the stomach
activate T cells to proliferate and secrete cytokines
survive within macrophages

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Microorganisms and Disease
Plastic implants can pose a serious nosocomial infection problem because

infected implants usually have to be surgically removed
phagocytes have trouble engulfing bacteria embedded in a biofilm
All of these
phagocytes have trouble moving on the plastic surface

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Microorganisms and Disease
What is common in catheters and ventilators?

They are used primarily in neonatal intensive care units
They bypass important defenses of the body
They predispose patients to viral rather than bacterial infections
Bacteria responsible for associated infections are usually susceptible to antibiotics

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