Recombinant DNA Technology
Which of the following is not true of small inbreeding populations?

Alleles may become fixed
Mutation is increased
They tend to loose genetic diversity
There is an increased incidence of recessive diseases

ANSWER DOWNLOAD EXAMIANS APP

Recombinant DNA Technology
Some genetic diseases cannot be diagnosed by changes in restriction sites. Some of these can be detected by allele-specific oligonucleotide probes. These are

PCR-amplified variable numbers of tandem repeats (VNTRs)
mutagenized copies of a gene
copies of the gene with an altered sequence so that a restriction site is inserted
short sequences that will hybridize only to a specific base sequence

ANSWER DOWNLOAD EXAMIANS APP

Recombinant DNA Technology
An expression vector

always contains DNA segments for the regulation of mRNA production
All of these
always contains an origin of replication
usually contains a gene that confers antibiotic resistance to the bacterial host

ANSWER DOWNLOAD EXAMIANS APP

Recombinant DNA Technology
Knockout mice are created by

infecting the mouse with a retrovirus
creating a chimera by fusing cells from two different cell lines
transfecting embryonic stem cells with an altered gene sequence
mutagenizing a mouse and selecting for mutant offspring

ANSWER DOWNLOAD EXAMIANS APP