Recombinant DNA Technology
Which of the following is not true of small inbreeding populations?

They tend to loose genetic diversity
Mutation is increased
There is an increased incidence of recessive diseases
Alleles may become fixed

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Recombinant DNA Technology
Knockout mice are created by

transfecting embryonic stem cells with an altered gene sequence
mutagenizing a mouse and selecting for mutant offspring
creating a chimera by fusing cells from two different cell lines
infecting the mouse with a retrovirus

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Recombinant DNA Technology
An expression vector

always contains an origin of replication
All of these
always contains DNA segments for the regulation of mRNA production
usually contains a gene that confers antibiotic resistance to the bacterial host

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