Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both require water to complete the catalytic cycle
Both show specificity for certain amino acid sequences
Both use nucleophilic attack to hydrolyze the peptide bond
Both forms an acyl-enzyme intermediate

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Enzymes
The E.coli pyruvic acid dehydrogenase complex is reported to

Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2
retard the reduction of pyruvic acid to acetyl Co A and CO2
Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

proximity of Ser 195 to the active site or specificity pocket
absence of water in the active site
size, shape, and charge of the active site or specificity pocket
presence of a low-barrier hydrogen bond in the active site or specificity pocket

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