Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

oxidizing the molecules by removing electrons
changing the reaction from a biosynthetic to a catabolic pathway
changing the three-dimensional shape of the molecule
the input of a small amount of activation energy

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Enzymes
In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)--->

A, B, and C will still be produced, but not D
A and B will still be produced, but not C or D
A, B, C, and D will all still be produced
A will still be produced, but not B, C, or D

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both forms an acyl-enzyme intermediate
Both use nucleophilic attack to hydrolyze the peptide bond
Both show specificity for certain amino acid sequences
Both require water to complete the catalytic cycle

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Enzymes
The E.coli pyruvic acid dehydrogenase complex is reported to

Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
retard the reduction of pyruvic acid to acetyl Co A and CO2
decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2

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