Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

changing the three-dimensional shape of the molecule
changing the reaction from a biosynthetic to a catabolic pathway
oxidizing the molecules by removing electrons
the input of a small amount of activation energy

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Enzymes
In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)--->

A, B, C, and D will all still be produced
A and B will still be produced, but not C or D
A will still be produced, but not B, C, or D
A, B, and C will still be produced, but not D

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both require water to complete the catalytic cycle
Both show specificity for certain amino acid sequences
Both forms an acyl-enzyme intermediate
Both use nucleophilic attack to hydrolyze the peptide bond

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Enzymes
The E.coli pyruvic acid dehydrogenase complex is reported to

Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2
retard the reduction of pyruvic acid to acetyl Co A and CO2
Catalyze the reduction of pyruvic acid to acetyl Co A and CO2

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