Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

changing the three-dimensional shape of the molecule
the input of a small amount of activation energy
oxidizing the molecules by removing electrons
changing the reaction from a biosynthetic to a catabolic pathway

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Enzymes
Which of the following statements about enzymes or their function is true?

All of these
Enzymes are proteins whose three-dimensional form is key to their function
Enzymes speed up reactions by lowering activation energy
Enzymes do not alter the overall change in free energy for a reaction

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

presence of a low-barrier hydrogen bond in the active site or specificity pocket
absence of water in the active site
proximity of Ser 195 to the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket

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