Enzymes Before they can react, many molecules need to be destabilized. This state is typically achieved through the input of a small amount of activation energy changing the three-dimensional shape of the molecule changing the reaction from a biosynthetic to a catabolic pathway oxidizing the molecules by removing electrons the input of a small amount of activation energy changing the three-dimensional shape of the molecule changing the reaction from a biosynthetic to a catabolic pathway oxidizing the molecules by removing electrons ANSWER DOWNLOAD EXAMIANS APP
Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket size, shape, and charge of the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket size, shape, and charge of the active site or specificity pocket absence of water in the active site ANSWER DOWNLOAD EXAMIANS APP
Enzymes Common feature in all serine proteases is a single reactive serine residue hydrophilic specificity pocket hydrophobic specificity pocket cluster of reactive serine residues single reactive serine residue hydrophilic specificity pocket hydrophobic specificity pocket cluster of reactive serine residues ANSWER DOWNLOAD EXAMIANS APP
Enzymes The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about 88 kJ/mol 49 kJ/mol 40 kJ/mol 58 kJ/mol 88 kJ/mol 49 kJ/mol 40 kJ/mol 58 kJ/mol ANSWER DOWNLOAD EXAMIANS APP
Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to neutralize the charge on the other's side chain clamp the substrate into the active site keep the specificity pocket open function as a proton shuttle neutralize the charge on the other's side chain clamp the substrate into the active site keep the specificity pocket open function as a proton shuttle ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following statements about enzymes or their function is true? Enzymes do not alter the overall change in free energy for a reaction Enzymes are proteins whose three-dimensional form is key to their function Enzymes speed up reactions by lowering activation energy All of these Enzymes do not alter the overall change in free energy for a reaction Enzymes are proteins whose three-dimensional form is key to their function Enzymes speed up reactions by lowering activation energy All of these ANSWER DOWNLOAD EXAMIANS APP