Enzymes
The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about

58 kJ/mol
88 kJ/mol
49 kJ/mol
40 kJ/mol

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Enzymes
The E.coli pyruvic acid dehydrogenase complex is reported to

Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2
Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
retard the reduction of pyruvic acid to acetyl Co A and CO2

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Enzymes
How is the enzyme COX-1 important in human health?

It catalyzes the production of hormones that maintain the stomach lining
It is critical for the biosynthesis of DNA
It helps to transport carbon dioxide in the blood
It is a chemical derivative of aspirin

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Enzymes
Which of the following statements about enzymes or their function is true?

Enzymes are proteins whose three-dimensional form is key to their function
All of these
Enzymes speed up reactions by lowering activation energy
Enzymes do not alter the overall change in free energy for a reaction

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

proximity of Ser 195 to the active site or specificity pocket
presence of a low-barrier hydrogen bond in the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket
absence of water in the active site

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

All of these
concentrating enzymes within specific cellular compartments
fixing enzymes into membranes so that they are adjacent to each other
grouping enzymes into free-floating, multienzyme complexes

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