Enzymes
The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about

88 kJ/mol
49 kJ/mol
58 kJ/mol
40 kJ/mol

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Enzymes
Which of the following statements about enzymes or their function is true?

All of these
Enzymes speed up reactions by lowering activation energy
Enzymes do not alter the overall change in free energy for a reaction
Enzymes are proteins whose three-dimensional form is key to their function

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Enzymes
In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)--->

A and B will still be produced, but not C or D
A, B, and C will still be produced, but not D
A will still be produced, but not B, C, or D
A, B, C, and D will all still be produced

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both forms an acyl-enzyme intermediate
Both use nucleophilic attack to hydrolyze the peptide bond
Both show specificity for certain amino acid sequences
Both require water to complete the catalytic cycle

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Enzymes
The E.coli pyruvic acid dehydrogenase complex is reported to

Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2
retard the reduction of pyruvic acid to acetyl Co A and CO2

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