Enzymes The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about 49 kJ/mol 40 kJ/mol 58 kJ/mol 88 kJ/mol 49 kJ/mol 40 kJ/mol 58 kJ/mol 88 kJ/mol ANSWER DOWNLOAD EXAMIANS APP
Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to neutralize the charge on the other's side chain function as a proton shuttle clamp the substrate into the active site keep the specificity pocket open neutralize the charge on the other's side chain function as a proton shuttle clamp the substrate into the active site keep the specificity pocket open ANSWER DOWNLOAD EXAMIANS APP
Enzymes The nucleophile in serine proteases is both (a) and (b) water Asparagine Serine both (a) and (b) water Asparagine Serine ANSWER DOWNLOAD EXAMIANS APP
Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket size, shape, and charge of the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket size, shape, and charge of the active site or specificity pocket absence of water in the active site ANSWER DOWNLOAD EXAMIANS APP
Enzymes Before they can react, many molecules need to be destabilized. This state is typically achieved through changing the reaction from a biosynthetic to a catabolic pathway the input of a small amount of activation energy oxidizing the molecules by removing electrons changing the three-dimensional shape of the molecule changing the reaction from a biosynthetic to a catabolic pathway the input of a small amount of activation energy oxidizing the molecules by removing electrons changing the three-dimensional shape of the molecule ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both forms an acyl-enzyme intermediate Both use nucleophilic attack to hydrolyze the peptide bond Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle Both forms an acyl-enzyme intermediate Both use nucleophilic attack to hydrolyze the peptide bond Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle ANSWER DOWNLOAD EXAMIANS APP
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