Enzymes The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about 40 kJ/mol 88 kJ/mol 58 kJ/mol 49 kJ/mol 40 kJ/mol 88 kJ/mol 58 kJ/mol 49 kJ/mol ANSWER DOWNLOAD EXAMIANS APP
Enzymes The nucleophile in serine proteases is both (a) and (b) Serine water Asparagine both (a) and (b) Serine water Asparagine ANSWER DOWNLOAD EXAMIANS APP
Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the proximity of Ser 195 to the active site or specificity pocket size, shape, and charge of the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket absence of water in the active site proximity of Ser 195 to the active site or specificity pocket size, shape, and charge of the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket absence of water in the active site ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following (s) is/are serine proteases? all of these Elastase Chymotrypsin Trypsin all of these Elastase Chymotrypsin Trypsin ANSWER DOWNLOAD EXAMIANS APP
Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to clamp the substrate into the active site keep the specificity pocket open neutralize the charge on the other's side chain function as a proton shuttle clamp the substrate into the active site keep the specificity pocket open neutralize the charge on the other's side chain function as a proton shuttle ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both forms an acyl-enzyme intermediate Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle Both use nucleophilic attack to hydrolyze the peptide bond Both forms an acyl-enzyme intermediate Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle Both use nucleophilic attack to hydrolyze the peptide bond ANSWER DOWNLOAD EXAMIANS APP
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