Enzymes
The E.coli pyruvic acid dehydrogenase complex is reported to

Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
retard the reduction of pyruvic acid to acetyl Co A and CO2
Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

grouping enzymes into free-floating, multienzyme complexes
All of these
fixing enzymes into membranes so that they are adjacent to each other
concentrating enzymes within specific cellular compartments

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