Enzymes
Which of the common features are shared between serine and aspartate proteases?

Both use a base to activate the nucleophile
Both require water to complete the catalytic cycle
Both show specificity for certain amino acid sequences
All of these

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Enzymes
How is the enzyme COX-1 important in human health?

It catalyzes the production of hormones that maintain the stomach lining
It is a chemical derivative of aspirin
It helps to transport carbon dioxide in the blood
It is critical for the biosynthesis of DNA

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

presence of a low-barrier hydrogen bond in the active site or specificity pocket
proximity of Ser 195 to the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket
absence of water in the active site

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Enzymes
Which of the following statements about enzymes or their function is true?

All of these
Enzymes speed up reactions by lowering activation energy
Enzymes do not alter the overall change in free energy for a reaction
Enzymes are proteins whose three-dimensional form is key to their function

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