Enzymes
Which of the common features are shared between serine and aspartate proteases?

All of these
Both require water to complete the catalytic cycle
Both show specificity for certain amino acid sequences
Both use a base to activate the nucleophile

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Enzymes
How is the enzyme COX-1 important in human health?

It helps to transport carbon dioxide in the blood
It is critical for the biosynthesis of DNA
It is a chemical derivative of aspirin
It catalyzes the production of hormones that maintain the stomach lining

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

size, shape, and charge of the active site or specificity pocket
absence of water in the active site
proximity of Ser 195 to the active site or specificity pocket
presence of a low-barrier hydrogen bond in the active site or specificity pocket

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

concentrating enzymes within specific cellular compartments
fixing enzymes into membranes so that they are adjacent to each other
grouping enzymes into free-floating, multienzyme complexes
All of these

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

changing the three-dimensional shape of the molecule
changing the reaction from a biosynthetic to a catabolic pathway
the input of a small amount of activation energy
oxidizing the molecules by removing electrons

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