Enzymes
Which of the common features are shared between serine and aspartate proteases?

Both show specificity for certain amino acid sequences
Both use a base to activate the nucleophile
Both require water to complete the catalytic cycle
All of these

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

proximity of Ser 195 to the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket
absence of water in the active site
presence of a low-barrier hydrogen bond in the active site or specificity pocket

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Enzymes
The E.coli pyruvic acid dehydrogenase complex is reported to

Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2
Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
retard the reduction of pyruvic acid to acetyl Co A and CO2

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