Enzymes
Which of the common features are shared between serine and aspartate proteases?

Both use a base to activate the nucleophile
All of these
Both require water to complete the catalytic cycle
Both show specificity for certain amino acid sequences

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

proximity of Ser 195 to the active site or specificity pocket
presence of a low-barrier hydrogen bond in the active site or specificity pocket
absence of water in the active site
size, shape, and charge of the active site or specificity pocket

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

grouping enzymes into free-floating, multienzyme complexes
fixing enzymes into membranes so that they are adjacent to each other
All of these
concentrating enzymes within specific cellular compartments

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

oxidizing the molecules by removing electrons
the input of a small amount of activation energy
changing the three-dimensional shape of the molecule
changing the reaction from a biosynthetic to a catabolic pathway

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