Enzymes
Which of the common features are shared between serine and aspartate proteases?

Both require water to complete the catalytic cycle
All of these
Both use a base to activate the nucleophile
Both show specificity for certain amino acid sequences

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Enzymes
How is the enzyme COX-1 important in human health?

It catalyzes the production of hormones that maintain the stomach lining
It helps to transport carbon dioxide in the blood
It is critical for the biosynthesis of DNA
It is a chemical derivative of aspirin

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Enzymes
Which of the following statements about enzymes or their function is true?

Enzymes do not alter the overall change in free energy for a reaction
Enzymes speed up reactions by lowering activation energy
Enzymes are proteins whose three-dimensional form is key to their function
All of these

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

absence of water in the active site
presence of a low-barrier hydrogen bond in the active site or specificity pocket
proximity of Ser 195 to the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

concentrating enzymes within specific cellular compartments
All of these
fixing enzymes into membranes so that they are adjacent to each other
grouping enzymes into free-floating, multienzyme complexes

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