Enzymes
Which of the common features are shared between serine and aspartate proteases?

Both use a base to activate the nucleophile
All of these
Both show specificity for certain amino acid sequences
Both require water to complete the catalytic cycle

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Enzymes
In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)--->

A, B, and C will still be produced, but not D
A will still be produced, but not B, C, or D
A and B will still be produced, but not C or D
A, B, C, and D will all still be produced

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both show specificity for certain amino acid sequences
Both use nucleophilic attack to hydrolyze the peptide bond
Both forms an acyl-enzyme intermediate
Both require water to complete the catalytic cycle

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Enzymes
Which of the following statements about enzymes or their function is true?

Enzymes do not alter the overall change in free energy for a reaction
All of these
Enzymes are proteins whose three-dimensional form is key to their function
Enzymes speed up reactions by lowering activation energy

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