Enzymes
Which of the common features are shared between serine and aspartate proteases?

Both use a base to activate the nucleophile
Both require water to complete the catalytic cycle
Both show specificity for certain amino acid sequences
All of these

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Enzymes
In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)--->

A and B will still be produced, but not C or D
A, B, and C will still be produced, but not D
A will still be produced, but not B, C, or D
A, B, C, and D will all still be produced

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both use nucleophilic attack to hydrolyze the peptide bond
Both show specificity for certain amino acid sequences
Both require water to complete the catalytic cycle
Both forms an acyl-enzyme intermediate

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