Enzymes Which of the common features are shared between serine and aspartate proteases? Both use a base to activate the nucleophile All of these Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences Both use a base to activate the nucleophile All of these Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences ANSWER DOWNLOAD EXAMIANS APP
Enzymes Tryprotophan synthetase of E.coli, a typical bifunctional oligomeric enzyme consist of a protein designated B a protein designated A two proteins designated A and B a protein A and one-subunit a a protein designated B a protein designated A two proteins designated A and B a protein A and one-subunit a ANSWER DOWNLOAD EXAMIANS APP
Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the size, shape, and charge of the active site or specificity pocket absence of water in the active site proximity of Ser 195 to the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket size, shape, and charge of the active site or specificity pocket absence of water in the active site proximity of Ser 195 to the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket ANSWER DOWNLOAD EXAMIANS APP
Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to clamp the substrate into the active site neutralize the charge on the other's side chain function as a proton shuttle keep the specificity pocket open clamp the substrate into the active site neutralize the charge on the other's side chain function as a proton shuttle keep the specificity pocket open ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences Both use nucleophilic attack to hydrolyze the peptide bond Both forms an acyl-enzyme intermediate Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences Both use nucleophilic attack to hydrolyze the peptide bond Both forms an acyl-enzyme intermediate ANSWER DOWNLOAD EXAMIANS APP
Enzymes The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about 88 kJ/mol 40 kJ/mol 49 kJ/mol 58 kJ/mol 88 kJ/mol 40 kJ/mol 49 kJ/mol 58 kJ/mol ANSWER DOWNLOAD EXAMIANS APP
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