Enzymes
Which of the following statements about enzymes or their function is true?

Enzymes do not alter the overall change in free energy for a reaction
Enzymes are proteins whose three-dimensional form is key to their function
Enzymes speed up reactions by lowering activation energy
All of these

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both require water to complete the catalytic cycle
Both show specificity for certain amino acid sequences
Both forms an acyl-enzyme intermediate
Both use nucleophilic attack to hydrolyze the peptide bond

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

All of these
fixing enzymes into membranes so that they are adjacent to each other
concentrating enzymes within specific cellular compartments
grouping enzymes into free-floating, multienzyme complexes

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

presence of a low-barrier hydrogen bond in the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket
absence of water in the active site
proximity of Ser 195 to the active site or specificity pocket

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