Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the size, shape, and charge of the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket absence of water in the active site size, shape, and charge of the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket absence of water in the active site ANSWER DOWNLOAD EXAMIANS APP
Enzymes Common feature in all serine proteases is a hydrophobic specificity pocket single reactive serine residue cluster of reactive serine residues hydrophilic specificity pocket hydrophobic specificity pocket single reactive serine residue cluster of reactive serine residues hydrophilic specificity pocket ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the common features are shared between serine and aspartate proteases? Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle All of these Both use a base to activate the nucleophile Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle All of these Both use a base to activate the nucleophile ANSWER DOWNLOAD EXAMIANS APP
Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to function as a proton shuttle clamp the substrate into the active site keep the specificity pocket open neutralize the charge on the other's side chain function as a proton shuttle clamp the substrate into the active site keep the specificity pocket open neutralize the charge on the other's side chain ANSWER DOWNLOAD EXAMIANS APP
Enzymes Enzyme-driven metabolic pathways can be made more efficient by All of these fixing enzymes into membranes so that they are adjacent to each other grouping enzymes into free-floating, multienzyme complexes concentrating enzymes within specific cellular compartments All of these fixing enzymes into membranes so that they are adjacent to each other grouping enzymes into free-floating, multienzyme complexes concentrating enzymes within specific cellular compartments ANSWER DOWNLOAD EXAMIANS APP
Enzymes In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)---> A, B, C, and D will all still be produced A, B, and C will still be produced, but not D A will still be produced, but not B, C, or D A and B will still be produced, but not C or D A, B, C, and D will all still be produced A, B, and C will still be produced, but not D A will still be produced, but not B, C, or D A and B will still be produced, but not C or D ANSWER DOWNLOAD EXAMIANS APP
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