Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

proximity of Ser 195 to the active site or specificity pocket
absence of water in the active site
presence of a low-barrier hydrogen bond in the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

changing the reaction from a biosynthetic to a catabolic pathway
oxidizing the molecules by removing electrons
the input of a small amount of activation energy
changing the three-dimensional shape of the molecule

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Enzymes
How is the enzyme COX-1 important in human health?

It is critical for the biosynthesis of DNA
It helps to transport carbon dioxide in the blood
It is a chemical derivative of aspirin
It catalyzes the production of hormones that maintain the stomach lining

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

All of these
concentrating enzymes within specific cellular compartments
fixing enzymes into membranes so that they are adjacent to each other
grouping enzymes into free-floating, multienzyme complexes

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