Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

absence of water in the active site
presence of a low-barrier hydrogen bond in the active site or specificity pocket
proximity of Ser 195 to the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket

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Enzymes
In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)--->

A and B will still be produced, but not C or D
A will still be produced, but not B, C, or D
A, B, and C will still be produced, but not D
A, B, C, and D will all still be produced

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

concentrating enzymes within specific cellular compartments
All of these
fixing enzymes into membranes so that they are adjacent to each other
grouping enzymes into free-floating, multienzyme complexes

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Enzymes
How is the enzyme COX-1 important in human health?

It catalyzes the production of hormones that maintain the stomach lining
It helps to transport carbon dioxide in the blood
It is a chemical derivative of aspirin
It is critical for the biosynthesis of DNA

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