Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the size, shape, and charge of the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket size, shape, and charge of the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the common features are shared between serine and aspartate proteases? Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences All of these Both use a base to activate the nucleophile Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences All of these Both use a base to activate the nucleophile ANSWER DOWNLOAD EXAMIANS APP
Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to clamp the substrate into the active site function as a proton shuttle neutralize the charge on the other's side chain keep the specificity pocket open clamp the substrate into the active site function as a proton shuttle neutralize the charge on the other's side chain keep the specificity pocket open ANSWER DOWNLOAD EXAMIANS APP
Enzymes The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about 49 kJ/mol 88 kJ/mol 58 kJ/mol 40 kJ/mol 49 kJ/mol 88 kJ/mol 58 kJ/mol 40 kJ/mol ANSWER DOWNLOAD EXAMIANS APP
Enzymes The E.coli pyruvic acid dehydrogenase complex is reported to decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2 retard the reduction of pyruvic acid to acetyl Co A and CO2 Catalyze the reduction of pyruvic acid to acetyl Co A and CO2 Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2 decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2 retard the reduction of pyruvic acid to acetyl Co A and CO2 Catalyze the reduction of pyruvic acid to acetyl Co A and CO2 Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2 ANSWER DOWNLOAD EXAMIANS APP
Enzymes Before they can react, many molecules need to be destabilized. This state is typically achieved through changing the three-dimensional shape of the molecule the input of a small amount of activation energy changing the reaction from a biosynthetic to a catabolic pathway oxidizing the molecules by removing electrons changing the three-dimensional shape of the molecule the input of a small amount of activation energy changing the reaction from a biosynthetic to a catabolic pathway oxidizing the molecules by removing electrons ANSWER DOWNLOAD EXAMIANS APP
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