Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket size, shape, and charge of the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket size, shape, and charge of the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket ANSWER DOWNLOAD EXAMIANS APP
Enzymes The nucleophile in serine proteases is Serine Asparagine water both (a) and (b) Serine Asparagine water both (a) and (b) ANSWER DOWNLOAD EXAMIANS APP
Enzymes How is the enzyme COX-1 important in human health? It helps to transport carbon dioxide in the blood It is a chemical derivative of aspirin It catalyzes the production of hormones that maintain the stomach lining It is critical for the biosynthesis of DNA It helps to transport carbon dioxide in the blood It is a chemical derivative of aspirin It catalyzes the production of hormones that maintain the stomach lining It is critical for the biosynthesis of DNA ANSWER DOWNLOAD EXAMIANS APP
Enzymes Common feature in all serine proteases is a cluster of reactive serine residues hydrophobic specificity pocket hydrophilic specificity pocket single reactive serine residue cluster of reactive serine residues hydrophobic specificity pocket hydrophilic specificity pocket single reactive serine residue ANSWER DOWNLOAD EXAMIANS APP
Enzymes The E.coli pyruvic acid dehydrogenase complex is reported to decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2 Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2 Catalyze the reduction of pyruvic acid to acetyl Co A and CO2 retard the reduction of pyruvic acid to acetyl Co A and CO2 decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2 Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2 Catalyze the reduction of pyruvic acid to acetyl Co A and CO2 retard the reduction of pyruvic acid to acetyl Co A and CO2 ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences Both forms an acyl-enzyme intermediate Both use nucleophilic attack to hydrolyze the peptide bond Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences Both forms an acyl-enzyme intermediate Both use nucleophilic attack to hydrolyze the peptide bond ANSWER DOWNLOAD EXAMIANS APP