Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

absence of water in the active site
proximity of Ser 195 to the active site or specificity pocket
presence of a low-barrier hydrogen bond in the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket

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Enzymes
In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)--->

A, B, C, and D will all still be produced
A will still be produced, but not B, C, or D
A, B, and C will still be produced, but not D
A and B will still be produced, but not C or D

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Enzymes
How is the enzyme COX-1 important in human health?

It is critical for the biosynthesis of DNA
It catalyzes the production of hormones that maintain the stomach lining
It helps to transport carbon dioxide in the blood
It is a chemical derivative of aspirin

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

fixing enzymes into membranes so that they are adjacent to each other
grouping enzymes into free-floating, multienzyme complexes
All of these
concentrating enzymes within specific cellular compartments

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Enzymes
The E.coli pyruvic acid dehydrogenase complex is reported to

Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
retard the reduction of pyruvic acid to acetyl Co A and CO2
decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2

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