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Enzymes

Enzymes
The nucleophile in serine proteases is

both (a) and (b)
Asparagine
water
Serine

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Enzymes
Tryprotophan synthetase of E.coli, a typical bifunctional oligomeric enzyme consist of

a protein designated B
a protein A and one-subunit a
a protein designated A
two proteins designated A and B

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Enzymes
Which of the following (s) is/are serine proteases?

all of these
Chymotrypsin
Elastase
Trypsin

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Enzymes
The role of Asp 102 and His 57 during trypsin catalysis is to

keep the specificity pocket open
neutralize the charge on the other's side chain
function as a proton shuttle
clamp the substrate into the active site

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Enzymes
Common feature in all serine proteases is a

hydrophobic specificity pocket
single reactive serine residue
cluster of reactive serine residues
hydrophilic specificity pocket

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Enzymes
Which of the common features are shared between serine and aspartate proteases?

All of these
Both use a base to activate the nucleophile
Both require water to complete the catalytic cycle
Both show specificity for certain amino acid sequences

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