Enzymes
Tryprotophan synthetase of E.coli, a typical bifunctional oligomeric enzyme consist of

a protein A and one-subunit a
a protein designated B
two proteins designated A and B
a protein designated A

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

presence of a low-barrier hydrogen bond in the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket
absence of water in the active site
proximity of Ser 195 to the active site or specificity pocket

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both show specificity for certain amino acid sequences
Both forms an acyl-enzyme intermediate
Both require water to complete the catalytic cycle
Both use nucleophilic attack to hydrolyze the peptide bond

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Enzymes
The E.coli pyruvic acid dehydrogenase complex is reported to

Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2
Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
retard the reduction of pyruvic acid to acetyl Co A and CO2

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