Enzymes
Tryprotophan synthetase of E.coli, a typical bifunctional oligomeric enzyme consist of

a protein designated A
a protein A and one-subunit a
two proteins designated A and B
a protein designated B

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Enzymes
In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)--->

A, B, C, and D will all still be produced
A and B will still be produced, but not C or D
A will still be produced, but not B, C, or D
A, B, and C will still be produced, but not D

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

presence of a low-barrier hydrogen bond in the active site or specificity pocket
absence of water in the active site
proximity of Ser 195 to the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket

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Enzymes
How is the enzyme COX-1 important in human health?

It is critical for the biosynthesis of DNA
It catalyzes the production of hormones that maintain the stomach lining
It is a chemical derivative of aspirin
It helps to transport carbon dioxide in the blood

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

the input of a small amount of activation energy
changing the three-dimensional shape of the molecule
oxidizing the molecules by removing electrons
changing the reaction from a biosynthetic to a catabolic pathway

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