Enzymes
Tryprotophan synthetase of E.coli, a typical bifunctional oligomeric enzyme consist of

two proteins designated A and B
a protein designated B
a protein A and one-subunit a
a protein designated A

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Enzymes
Which of the following statements about enzymes or their function is true?

All of these
Enzymes do not alter the overall change in free energy for a reaction
Enzymes are proteins whose three-dimensional form is key to their function
Enzymes speed up reactions by lowering activation energy

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

size, shape, and charge of the active site or specificity pocket
proximity of Ser 195 to the active site or specificity pocket
absence of water in the active site
presence of a low-barrier hydrogen bond in the active site or specificity pocket

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

concentrating enzymes within specific cellular compartments
fixing enzymes into membranes so that they are adjacent to each other
All of these
grouping enzymes into free-floating, multienzyme complexes

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both use nucleophilic attack to hydrolyze the peptide bond
Both require water to complete the catalytic cycle
Both show specificity for certain amino acid sequences
Both forms an acyl-enzyme intermediate

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