Enzymes
Tryprotophan synthetase of E.coli, a typical bifunctional oligomeric enzyme consist of

a protein A and one-subunit a
a protein designated B
two proteins designated A and B
a protein designated A

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

the input of a small amount of activation energy
changing the reaction from a biosynthetic to a catabolic pathway
changing the three-dimensional shape of the molecule
oxidizing the molecules by removing electrons

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

size, shape, and charge of the active site or specificity pocket
absence of water in the active site
proximity of Ser 195 to the active site or specificity pocket
presence of a low-barrier hydrogen bond in the active site or specificity pocket

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