Enzymes
The role of Asp 102 and His 57 during trypsin catalysis is to

clamp the substrate into the active site
neutralize the charge on the other's side chain
keep the specificity pocket open
function as a proton shuttle

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Enzymes
The E.coli pyruvic acid dehydrogenase complex is reported to

retard the reduction of pyruvic acid to acetyl Co A and CO2
Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2
decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

fixing enzymes into membranes so that they are adjacent to each other
grouping enzymes into free-floating, multienzyme complexes
concentrating enzymes within specific cellular compartments
All of these

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Enzymes
In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)--->

A, B, C, and D will all still be produced
A will still be produced, but not B, C, or D
A, B, and C will still be produced, but not D
A and B will still be produced, but not C or D

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

changing the reaction from a biosynthetic to a catabolic pathway
changing the three-dimensional shape of the molecule
the input of a small amount of activation energy
oxidizing the molecules by removing electrons

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