Enzymes
The role of Asp 102 and His 57 during trypsin catalysis is to

neutralize the charge on the other's side chain
function as a proton shuttle
clamp the substrate into the active site
keep the specificity pocket open

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

fixing enzymes into membranes so that they are adjacent to each other
All of these
concentrating enzymes within specific cellular compartments
grouping enzymes into free-floating, multienzyme complexes

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both show specificity for certain amino acid sequences
Both forms an acyl-enzyme intermediate
Both require water to complete the catalytic cycle
Both use nucleophilic attack to hydrolyze the peptide bond

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Enzymes
How is the enzyme COX-1 important in human health?

It catalyzes the production of hormones that maintain the stomach lining
It is critical for the biosynthesis of DNA
It is a chemical derivative of aspirin
It helps to transport carbon dioxide in the blood

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

changing the three-dimensional shape of the molecule
changing the reaction from a biosynthetic to a catabolic pathway
oxidizing the molecules by removing electrons
the input of a small amount of activation energy

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