Enzymes
The role of Asp 102 and His 57 during trypsin catalysis is to

neutralize the charge on the other's side chain
clamp the substrate into the active site
keep the specificity pocket open
function as a proton shuttle

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Enzymes
Which of the following statements about enzymes or their function is true?

Enzymes do not alter the overall change in free energy for a reaction
Enzymes speed up reactions by lowering activation energy
Enzymes are proteins whose three-dimensional form is key to their function
All of these

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