Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to keep the specificity pocket open clamp the substrate into the active site neutralize the charge on the other's side chain function as a proton shuttle keep the specificity pocket open clamp the substrate into the active site neutralize the charge on the other's side chain function as a proton shuttle ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the common features are shared between serine and aspartate proteases? Both show specificity for certain amino acid sequences All of these Both use a base to activate the nucleophile Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences All of these Both use a base to activate the nucleophile Both require water to complete the catalytic cycle ANSWER DOWNLOAD EXAMIANS APP
Enzymes Common feature in all serine proteases is a hydrophilic specificity pocket cluster of reactive serine residues single reactive serine residue hydrophobic specificity pocket hydrophilic specificity pocket cluster of reactive serine residues single reactive serine residue hydrophobic specificity pocket ANSWER DOWNLOAD EXAMIANS APP
Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the absence of water in the active site proximity of Ser 195 to the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket size, shape, and charge of the active site or specificity pocket absence of water in the active site proximity of Ser 195 to the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket size, shape, and charge of the active site or specificity pocket ANSWER DOWNLOAD EXAMIANS APP
Enzymes In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)---> A will still be produced, but not B, C, or D A and B will still be produced, but not C or D A, B, C, and D will all still be produced A, B, and C will still be produced, but not D A will still be produced, but not B, C, or D A and B will still be produced, but not C or D A, B, C, and D will all still be produced A, B, and C will still be produced, but not D ANSWER DOWNLOAD EXAMIANS APP
Enzymes What is the specificity of the Clostripain protease? None of these It cleave after Lys residues It cleave after His residues It cleave after Arg residues None of these It cleave after Lys residues It cleave after His residues It cleave after Arg residues ANSWER DOWNLOAD EXAMIANS APP