Enzymes
The role of Asp 102 and His 57 during trypsin catalysis is to

function as a proton shuttle
keep the specificity pocket open
clamp the substrate into the active site
neutralize the charge on the other's side chain

ANSWER DOWNLOAD EXAMIANS APP

Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

absence of water in the active site
proximity of Ser 195 to the active site or specificity pocket
presence of a low-barrier hydrogen bond in the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket

ANSWER DOWNLOAD EXAMIANS APP

Enzymes
How is the enzyme COX-1 important in human health?

It catalyzes the production of hormones that maintain the stomach lining
It helps to transport carbon dioxide in the blood
It is critical for the biosynthesis of DNA
It is a chemical derivative of aspirin

ANSWER DOWNLOAD EXAMIANS APP

Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

grouping enzymes into free-floating, multienzyme complexes
All of these
concentrating enzymes within specific cellular compartments
fixing enzymes into membranes so that they are adjacent to each other

ANSWER DOWNLOAD EXAMIANS APP

Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both forms an acyl-enzyme intermediate
Both use nucleophilic attack to hydrolyze the peptide bond
Both show specificity for certain amino acid sequences
Both require water to complete the catalytic cycle

ANSWER DOWNLOAD EXAMIANS APP