Enzymes
The role of Asp 102 and His 57 during trypsin catalysis is to

keep the specificity pocket open
neutralize the charge on the other's side chain
function as a proton shuttle
clamp the substrate into the active site

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Enzymes
How is the enzyme COX-1 important in human health?

It helps to transport carbon dioxide in the blood
It is critical for the biosynthesis of DNA
It is a chemical derivative of aspirin
It catalyzes the production of hormones that maintain the stomach lining

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both forms an acyl-enzyme intermediate
Both require water to complete the catalytic cycle
Both show specificity for certain amino acid sequences
Both use nucleophilic attack to hydrolyze the peptide bond

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Enzymes
In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)--->

A and B will still be produced, but not C or D
A, B, and C will still be produced, but not D
A will still be produced, but not B, C, or D
A, B, C, and D will all still be produced

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