Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to neutralize the charge on the other's side chain keep the specificity pocket open clamp the substrate into the active site function as a proton shuttle neutralize the charge on the other's side chain keep the specificity pocket open clamp the substrate into the active site function as a proton shuttle ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both require water to complete the catalytic cycle Both forms an acyl-enzyme intermediate Both show specificity for certain amino acid sequences Both use nucleophilic attack to hydrolyze the peptide bond Both require water to complete the catalytic cycle Both forms an acyl-enzyme intermediate Both show specificity for certain amino acid sequences Both use nucleophilic attack to hydrolyze the peptide bond ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following (s) is/are serine proteases? Elastase Chymotrypsin Trypsin all of these Elastase Chymotrypsin Trypsin all of these ANSWER DOWNLOAD EXAMIANS APP
Enzymes The E.coli pyruvic acid dehydrogenase complex is reported to decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2 retard the reduction of pyruvic acid to acetyl Co A and CO2 Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2 Catalyze the reduction of pyruvic acid to acetyl Co A and CO2 decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2 retard the reduction of pyruvic acid to acetyl Co A and CO2 Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2 Catalyze the reduction of pyruvic acid to acetyl Co A and CO2 ANSWER DOWNLOAD EXAMIANS APP
Enzymes In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)---> A and B will still be produced, but not C or D A, B, and C will still be produced, but not D A, B, C, and D will all still be produced A will still be produced, but not B, C, or D A and B will still be produced, but not C or D A, B, and C will still be produced, but not D A, B, C, and D will all still be produced A will still be produced, but not B, C, or D ANSWER DOWNLOAD EXAMIANS APP
Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket size, shape, and charge of the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket size, shape, and charge of the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket ANSWER DOWNLOAD EXAMIANS APP