Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to clamp the substrate into the active site keep the specificity pocket open function as a proton shuttle neutralize the charge on the other's side chain clamp the substrate into the active site keep the specificity pocket open function as a proton shuttle neutralize the charge on the other's side chain ANSWER DOWNLOAD EXAMIANS APP
Enzymes The nucleophile in serine proteases is water Asparagine both (a) and (b) Serine water Asparagine both (a) and (b) Serine ANSWER DOWNLOAD EXAMIANS APP
Enzymes Common feature in all serine proteases is a hydrophobic specificity pocket cluster of reactive serine residues single reactive serine residue hydrophilic specificity pocket hydrophobic specificity pocket cluster of reactive serine residues single reactive serine residue hydrophilic specificity pocket ANSWER DOWNLOAD EXAMIANS APP
Enzymes In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)---> A and B will still be produced, but not C or D A, B, C, and D will all still be produced A will still be produced, but not B, C, or D A, B, and C will still be produced, but not D A and B will still be produced, but not C or D A, B, C, and D will all still be produced A will still be produced, but not B, C, or D A, B, and C will still be produced, but not D ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both use nucleophilic attack to hydrolyze the peptide bond Both require water to complete the catalytic cycle Both forms an acyl-enzyme intermediate Both show specificity for certain amino acid sequences Both use nucleophilic attack to hydrolyze the peptide bond Both require water to complete the catalytic cycle Both forms an acyl-enzyme intermediate Both show specificity for certain amino acid sequences ANSWER DOWNLOAD EXAMIANS APP
Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the size, shape, and charge of the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket size, shape, and charge of the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket ANSWER DOWNLOAD EXAMIANS APP
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