Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to neutralize the charge on the other's side chain clamp the substrate into the active site function as a proton shuttle keep the specificity pocket open neutralize the charge on the other's side chain clamp the substrate into the active site function as a proton shuttle keep the specificity pocket open ANSWER DOWNLOAD EXAMIANS APP
Enzymes How is the enzyme COX-1 important in human health? It catalyzes the production of hormones that maintain the stomach lining It helps to transport carbon dioxide in the blood It is a chemical derivative of aspirin It is critical for the biosynthesis of DNA It catalyzes the production of hormones that maintain the stomach lining It helps to transport carbon dioxide in the blood It is a chemical derivative of aspirin It is critical for the biosynthesis of DNA ANSWER DOWNLOAD EXAMIANS APP
Enzymes The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about 88 kJ/mol 40 kJ/mol 58 kJ/mol 49 kJ/mol 88 kJ/mol 40 kJ/mol 58 kJ/mol 49 kJ/mol ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both require water to complete the catalytic cycle Both use nucleophilic attack to hydrolyze the peptide bond Both forms an acyl-enzyme intermediate Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle Both use nucleophilic attack to hydrolyze the peptide bond Both forms an acyl-enzyme intermediate Both show specificity for certain amino acid sequences ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the common features are shared between serine and aspartate proteases? Both use a base to activate the nucleophile Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences All of these Both use a base to activate the nucleophile Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences All of these ANSWER DOWNLOAD EXAMIANS APP
Enzymes Common feature in all serine proteases is a hydrophilic specificity pocket cluster of reactive serine residues single reactive serine residue hydrophobic specificity pocket hydrophilic specificity pocket cluster of reactive serine residues single reactive serine residue hydrophobic specificity pocket ANSWER DOWNLOAD EXAMIANS APP