Enzymes
The role of Asp 102 and His 57 during trypsin catalysis is to

function as a proton shuttle
clamp the substrate into the active site
keep the specificity pocket open
neutralize the charge on the other's side chain

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both require water to complete the catalytic cycle
Both use nucleophilic attack to hydrolyze the peptide bond
Both show specificity for certain amino acid sequences
Both forms an acyl-enzyme intermediate

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

fixing enzymes into membranes so that they are adjacent to each other
grouping enzymes into free-floating, multienzyme complexes
All of these
concentrating enzymes within specific cellular compartments

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Enzymes
The E.coli pyruvic acid dehydrogenase complex is reported to

decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2
Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
retard the reduction of pyruvic acid to acetyl Co A and CO2
Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2

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