Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to function as a proton shuttle keep the specificity pocket open neutralize the charge on the other's side chain clamp the substrate into the active site function as a proton shuttle keep the specificity pocket open neutralize the charge on the other's side chain clamp the substrate into the active site ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both forms an acyl-enzyme intermediate Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle Both use nucleophilic attack to hydrolyze the peptide bond Both forms an acyl-enzyme intermediate Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle Both use nucleophilic attack to hydrolyze the peptide bond ANSWER DOWNLOAD EXAMIANS APP
Enzymes What is the specificity of the Clostripain protease? It cleave after Lys residues It cleave after His residues It cleave after Arg residues None of these It cleave after Lys residues It cleave after His residues It cleave after Arg residues None of these ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the common features are shared between serine and aspartate proteases? Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences All of these Both use a base to activate the nucleophile Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences All of these Both use a base to activate the nucleophile ANSWER DOWNLOAD EXAMIANS APP
Enzymes The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about 40 kJ/mol 88 kJ/mol 49 kJ/mol 58 kJ/mol 40 kJ/mol 88 kJ/mol 49 kJ/mol 58 kJ/mol ANSWER DOWNLOAD EXAMIANS APP
Enzymes In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)---> A, B, C, and D will all still be produced A and B will still be produced, but not C or D A will still be produced, but not B, C, or D A, B, and C will still be produced, but not D A, B, C, and D will all still be produced A and B will still be produced, but not C or D A will still be produced, but not B, C, or D A, B, and C will still be produced, but not D ANSWER DOWNLOAD EXAMIANS APP
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