Enzymes
The role of Asp 102 and His 57 during trypsin catalysis is to

keep the specificity pocket open
function as a proton shuttle
neutralize the charge on the other's side chain
clamp the substrate into the active site

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

presence of a low-barrier hydrogen bond in the active site or specificity pocket
proximity of Ser 195 to the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket
absence of water in the active site

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Enzymes
How is the enzyme COX-1 important in human health?

It is a chemical derivative of aspirin
It catalyzes the production of hormones that maintain the stomach lining
It helps to transport carbon dioxide in the blood
It is critical for the biosynthesis of DNA

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

changing the reaction from a biosynthetic to a catabolic pathway
changing the three-dimensional shape of the molecule
oxidizing the molecules by removing electrons
the input of a small amount of activation energy

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Enzymes
Which of the following statements about enzymes or their function is true?

Enzymes are proteins whose three-dimensional form is key to their function
Enzymes speed up reactions by lowering activation energy
Enzymes do not alter the overall change in free energy for a reaction
All of these

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