Enzymes
The role of Asp 102 and His 57 during trypsin catalysis is to

neutralize the charge on the other's side chain
clamp the substrate into the active site
function as a proton shuttle
keep the specificity pocket open

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Enzymes
How is the enzyme COX-1 important in human health?

It catalyzes the production of hormones that maintain the stomach lining
It helps to transport carbon dioxide in the blood
It is a chemical derivative of aspirin
It is critical for the biosynthesis of DNA

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both require water to complete the catalytic cycle
Both use nucleophilic attack to hydrolyze the peptide bond
Both forms an acyl-enzyme intermediate
Both show specificity for certain amino acid sequences

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