Enzymes
The role of Asp 102 and His 57 during trypsin catalysis is to

keep the specificity pocket open
neutralize the charge on the other's side chain
function as a proton shuttle
clamp the substrate into the active site

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Enzymes
How is the enzyme COX-1 important in human health?

It catalyzes the production of hormones that maintain the stomach lining
It is critical for the biosynthesis of DNA
It helps to transport carbon dioxide in the blood
It is a chemical derivative of aspirin

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

changing the three-dimensional shape of the molecule
the input of a small amount of activation energy
oxidizing the molecules by removing electrons
changing the reaction from a biosynthetic to a catabolic pathway

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Enzymes
The E.coli pyruvic acid dehydrogenase complex is reported to

retard the reduction of pyruvic acid to acetyl Co A and CO2
Catalyze the reduction of pyruvic acid to acetyl Co A and CO2
decatalyze the oxidation of pyruvic acid to acetyl Co A and CO2
Catalyze the oxidation of pyruvic acid to acetyl Co A and CO2

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

All of these
grouping enzymes into free-floating, multienzyme complexes
concentrating enzymes within specific cellular compartments
fixing enzymes into membranes so that they are adjacent to each other

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