Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

grouping enzymes into free-floating, multienzyme complexes
fixing enzymes into membranes so that they are adjacent to each other
concentrating enzymes within specific cellular compartments
All of these

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Enzymes
How is the enzyme COX-1 important in human health?

It catalyzes the production of hormones that maintain the stomach lining
It is a chemical derivative of aspirin
It is critical for the biosynthesis of DNA
It helps to transport carbon dioxide in the blood

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

changing the three-dimensional shape of the molecule
oxidizing the molecules by removing electrons
the input of a small amount of activation energy
changing the reaction from a biosynthetic to a catabolic pathway

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both use nucleophilic attack to hydrolyze the peptide bond
Both require water to complete the catalytic cycle
Both forms an acyl-enzyme intermediate
Both show specificity for certain amino acid sequences

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

absence of water in the active site
size, shape, and charge of the active site or specificity pocket
presence of a low-barrier hydrogen bond in the active site or specificity pocket
proximity of Ser 195 to the active site or specificity pocket

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Enzymes
Which of the following statements about enzymes or their function is true?

All of these
Enzymes do not alter the overall change in free energy for a reaction
Enzymes speed up reactions by lowering activation energy
Enzymes are proteins whose three-dimensional form is key to their function

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