Enzymes
How is the enzyme COX-1 important in human health?

It helps to transport carbon dioxide in the blood
It is a chemical derivative of aspirin
It is critical for the biosynthesis of DNA
It catalyzes the production of hormones that maintain the stomach lining

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Enzymes
Enzyme-driven metabolic pathways can be made more efficient by

grouping enzymes into free-floating, multienzyme complexes
concentrating enzymes within specific cellular compartments
fixing enzymes into membranes so that they are adjacent to each other
All of these

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

proximity of Ser 195 to the active site or specificity pocket
absence of water in the active site
size, shape, and charge of the active site or specificity pocket
presence of a low-barrier hydrogen bond in the active site or specificity pocket

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both require water to complete the catalytic cycle
Both forms an acyl-enzyme intermediate
Both show specificity for certain amino acid sequences
Both use nucleophilic attack to hydrolyze the peptide bond

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

oxidizing the molecules by removing electrons
the input of a small amount of activation energy
changing the reaction from a biosynthetic to a catabolic pathway
changing the three-dimensional shape of the molecule

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Enzymes
Which of the following statements about enzymes or their function is true?

All of these
Enzymes are proteins whose three-dimensional form is key to their function
Enzymes speed up reactions by lowering activation energy
Enzymes do not alter the overall change in free energy for a reaction

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