Enzymes Common feature in all serine proteases is a single reactive serine residue hydrophilic specificity pocket cluster of reactive serine residues hydrophobic specificity pocket single reactive serine residue hydrophilic specificity pocket cluster of reactive serine residues hydrophobic specificity pocket ANSWER DOWNLOAD EXAMIANS APP
Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the size, shape, and charge of the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket absence of water in the active site size, shape, and charge of the active site or specificity pocket presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket absence of water in the active site ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following (s) is/are serine proteases? Chymotrypsin all of these Elastase Trypsin Chymotrypsin all of these Elastase Trypsin ANSWER DOWNLOAD EXAMIANS APP
Enzymes The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about 49 kJ/mol 40 kJ/mol 58 kJ/mol 88 kJ/mol 49 kJ/mol 40 kJ/mol 58 kJ/mol 88 kJ/mol ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both forms an acyl-enzyme intermediate Both use nucleophilic attack to hydrolyze the peptide bond Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle Both forms an acyl-enzyme intermediate Both use nucleophilic attack to hydrolyze the peptide bond Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle ANSWER DOWNLOAD EXAMIANS APP
Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to clamp the substrate into the active site keep the specificity pocket open neutralize the charge on the other's side chain function as a proton shuttle clamp the substrate into the active site keep the specificity pocket open neutralize the charge on the other's side chain function as a proton shuttle ANSWER DOWNLOAD EXAMIANS APP
EXAMIANS