Enzymes
Common feature in all serine proteases is a

single reactive serine residue
hydrophobic specificity pocket
cluster of reactive serine residues
hydrophilic specificity pocket

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Enzymes
In the enzyme-catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2? A ---(E1)---> B ---(E2)---> C ---(E3)--->

A will still be produced, but not B, C, or D
A, B, and C will still be produced, but not D
A, B, C, and D will all still be produced
A and B will still be produced, but not C or D

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both use nucleophilic attack to hydrolyze the peptide bond
Both show specificity for certain amino acid sequences
Both require water to complete the catalytic cycle
Both forms an acyl-enzyme intermediate

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

oxidizing the molecules by removing electrons
changing the reaction from a biosynthetic to a catabolic pathway
changing the three-dimensional shape of the molecule
the input of a small amount of activation energy

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