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Animal Cell Culture and Regulation

Animal Cell Culture and Regulation
The human fibroplast is a classical example of

cell transformations
none of these
established cell lines
stable primary cell lines

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Animal Cell Culture and Regulation
Higher dissolved oxygen concentration in the culture media are toxic and lead to

DNA degradation
lipid peroxidation
All of these
metabolism of nutrients in culture media at a rate greater than that required for consumption

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Animal Cell Culture and Regulation
In animal cell culture, particularly mammalian cell culture, transformation means

both (a) and (b)
uptake of new genetic material
phenotypic modifications of cells in culture
release of genetic information

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Animal Cell Culture and Regulation
How does CO2 help in the cell metabolism during cell culture?

For monitoring pH of the culture
Helps in the cells respiration
All of these
It participates in the de novo synthesis of purines and pyrimidines

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Animal Cell Culture and Regulation
Which of the following abnormality, resulted from the inheritance of an unbalanced complement of chromosomes can be diagnosed through karotyping?

all of these
Turner's syndrome
Down's syndrome
Klinefelter's syndrome

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Animal Cell Culture and Regulation
Toxicity due to accumulation of ammonia can be overcome

All of these
by controlled addition of glutamine at low level
by substituting glutamine by glutamate
by removal of ammonia or ammonium from culture medium

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