Recombinant DNA Technology
Isoschizomers recognize

same recognition site and recognition sequence
different recognition site and different recognition sequence
same recognition site and different recognition sequence
same recognition sequence but different recognition site

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Recombinant DNA Technology
Knockout mice are created by

mutagenizing a mouse and selecting for mutant offspring
creating a chimera by fusing cells from two different cell lines
transfecting embryonic stem cells with an altered gene sequence
infecting the mouse with a retrovirus

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