Recombinant DNA Technology
Knockout mice are created by

mutagenizing a mouse and selecting for mutant offspring
infecting the mouse with a retrovirus
creating a chimera by fusing cells from two different cell lines
transfecting embryonic stem cells with an altered gene sequence

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Recombinant DNA Technology
An example of a restriction fragment length polymorphism is

an Eco RI cuts DNA at a different sequence than Hind III
different length fragments of DNA resulting from loss or gain of a restriction site
All of these
cystic fibrosis results from a three base deletion in most cases but in other cases, other mutations are involved

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Recombinant DNA Technology
Isoschizomers recognize

same recognition site and recognition sequence
same recognition sequence but different recognition site
same recognition site and different recognition sequence
different recognition site and different recognition sequence

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