Animal Cell Culture and Regulation
In animal cell culture, particularly mammalian cell culture, transformation means

release of genetic information
both (a) and (b)
uptake of new genetic material
phenotypic modifications of cells in culture

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Animal Cell Culture and Regulation
The major problem associated with the isolation of free cells and cell aggregates from organs is that of

inhibiting the cells from their supporting matrix
releasing the cells from their supporting matrix
disintegrating the cells from their supporting matrix
None of these

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