DNA Sequencing, Mutation and Repair
Frame shift mutation may occur as a result of

deamination of cytosine to uracil
conversion of guanine to xanthine
formation of a thymine-dimer
None of these

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DNA Sequencing, Mutation and Repair
The whole-genome shotgun sequencing approach depends primarily on

methodical sequencing a few large cloned fragments of DNA
sequencing the bacterial chromosome while it is still intact
All of these
rapidly sequencing thousands of small randomly cloned fragments

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