DNA Sequencing, Mutation and Repair
A nonsense mutation may result into

a premature termination of the synthesis of a polypeptide
a large deletion within the reading frame of a gene
an abnormal elongation of a polypeptide
modification of mRNA

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DNA Sequencing, Mutation and Repair
The whole-genome shotgun sequencing approach depends primarily on

methodical sequencing a few large cloned fragments of DNA
sequencing the bacterial chromosome while it is still intact
rapidly sequencing thousands of small randomly cloned fragments
All of these

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DNA Sequencing, Mutation and Repair
Due to which of the following DNA repair mechanisms, one is able to distinguish newly synthesized DNA strands from older one?

New strands do not contain cytosine bases
Old strands are methylated while new strands are not
New strands are methylated while old strands are not
New strands are lower in molecular size

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