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DNA Sequencing, Mutation and Repair

DNA Sequencing, Mutation and Repair
Changes in which of the following characterizes mutations?

Phenotype
Genotype
Both (a) and (b)
None of these

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DNA Sequencing, Mutation and Repair
A nonsense mutation introduced into the DNA sequence of a gene may

shorten the length of the protein encoded by the gene
have no effect on the transcript or protein made
cause premature termination of the mRNA
cause a shift in reading frame

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DNA Sequencing, Mutation and Repair
The mutation which will not affect the length of a protein is,

nonsense mutation
frameshift mutation
missense mutation
all of these

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DNA Sequencing, Mutation and Repair
Which of these mechanisms for thymine dimers repair lead to mutations?

SOS repair
Photoreactivation
Excision repair
Never leads to mutation

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DNA Sequencing, Mutation and Repair
Frame shift mutation may occur as a result of

None of these
conversion of guanine to xanthine
deamination of cytosine to uracil
formation of a thymine-dimer

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DNA Sequencing, Mutation and Repair
The promoter on an expression vector used to overproduce proteins in bacteria is

a bacterial promoter
the natural promoter of the gene being cloned
expressed both in bacteria and mammalian cells
not a regulated promoter

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