DNA Sequencing, Mutation and Repair
The whole-genome shotgun sequencing approach depends primarily on

All of these
sequencing the bacterial chromosome while it is still intact
methodical sequencing a few large cloned fragments of DNA
rapidly sequencing thousands of small randomly cloned fragments

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DNA Sequencing, Mutation and Repair
Due to which of the following DNA repair mechanisms, one is able to distinguish newly synthesized DNA strands from older one?

New strands are lower in molecular size
Old strands are methylated while new strands are not
New strands are methylated while old strands are not
New strands do not contain cytosine bases

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