Microorganisms and Disease
Each of the 3 virulence factors of Bacillus anthracis i.e. the capsule, edema toxin and lethal toxin can affect the activity of

B cells
macrophages
ciliated epithelial cells
M cells

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Microorganisms and Disease
Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine?

A limited number of capsule types
The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings
The possession of a segmented RNA genome
The ability of the Rotavirus to be transmitted faster

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Microorganisms and Disease
Cholera toxin is an A-B type toxin in which the B portions bind to a receptor on a host cell and the A portion enters the cell to cause

ADP ribosylation of a G protein that locks it into an active form that stimulates adenylate cyclase to make cAMP
ADP ribosylation of adenylate cyclase that stops production of cAMP
cleavage of rRNA that results in disruption of ribosome function
ADP ribosylation of guanylate cyclase that stimulates production of cGMP

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Microorganisms and Disease
Type III secretion systems are used to inject "effector" proteins directly into a host cell. Salmonella uses a type III secretion system to help the pathogen to

activate T cells to proliferate and secrete cytokines
survive the acid pH of the stomach
secrete LT (heat labile toxin) and ST (heat stable toxin) into the lumen of the intestine
survive within macrophages

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