Microorganisms and Disease
Both Mycobacterium tuberculosis and Streptococcus pneumoniae

are acquired by inhalation
have cell walls that contain a high content of mycolic acids
have polysaccharide capsules
stay in the lung and rarely, if ever, enter the bloodstream

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

cause ADP ribosylation of a factor involved in protein synthesis
binds host cell receptors found on heart cells
lysis macrophages with the release of cytokines
forms cAMP that leads to fluid accumulation

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