Microorganisms and Disease
Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine?

A limited number of capsule types
The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings
The possession of a segmented RNA genome
The ability of the Rotavirus to be transmitted faster

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Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

The most serious disease symptoms are the direct result of toxin action
Both organisms cause skin and respiratory tract infections
Diphtheria toxin and edema toxin are ADP ribosylating toxins
Both organisms are gram-positive spore formers

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Microorganisms and Disease
Plastic implants can pose a serious nosocomial infection problem because

phagocytes have trouble moving on the plastic surface
infected implants usually have to be surgically removed
phagocytes have trouble engulfing bacteria embedded in a biofilm
All of these

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

binds host cell receptors found on heart cells
cause ADP ribosylation of a factor involved in protein synthesis
forms cAMP that leads to fluid accumulation
lysis macrophages with the release of cytokines

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