Microorganisms and Disease
Fatalities following influenza infection are usually due to the

damage to the heart muscle
bacterial superinfection
dehydration
formation of granulomas in the lung

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Microorganisms and Disease
A major difference between EHEC and EPEC is

EHEC possesses a type III secretion system and EPEC does not
EPEC passes through the placenta to infect the fetus and EHEC does not
EPEC rearranges host cell actin and EHEC does not
EHEC secretes a Shiga-like toxin and EPEC does not

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Microorganisms and Disease
Which of the following is true regarding anthrax?

Inhalation Anthrax requires infection with a large number of spores
Inhalation anthrax and cutaneous anthrax are caused by separate strains of Bacillus anthracis
Anthrax is highly contagious
Anthrax is caused by a virus

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Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

Both organisms cause skin and respiratory tract infections
Diphtheria toxin and edema toxin are ADP ribosylating toxins
The most serious disease symptoms are the direct result of toxin action
Both organisms are gram-positive spore formers

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Microorganisms and Disease
Cholera toxin is an A-B type toxin in which the B portions bind to a receptor on a host cell and the A portion enters the cell to cause

ADP ribosylation of guanylate cyclase that stimulates production of cGMP
ADP ribosylation of a G protein that locks it into an active form that stimulates adenylate cyclase to make cAMP
cleavage of rRNA that results in disruption of ribosome function
ADP ribosylation of adenylate cyclase that stops production of cAMP

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