Microorganisms and Disease
Fatalities following influenza infection are usually due to the

dehydration
damage to the heart muscle
formation of granulomas in the lung
bacterial superinfection

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Microorganisms and Disease
Cholera toxin is an A-B type toxin in which the B portions bind to a receptor on a host cell and the A portion enters the cell to cause

ADP ribosylation of a G protein that locks it into an active form that stimulates adenylate cyclase to make cAMP
ADP ribosylation of adenylate cyclase that stops production of cAMP
ADP ribosylation of guanylate cyclase that stimulates production of cGMP
cleavage of rRNA that results in disruption of ribosome function

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Microorganisms and Disease
A major difference between EHEC and EPEC is

EHEC secretes a Shiga-like toxin and EPEC does not
EHEC possesses a type III secretion system and EPEC does not
EPEC passes through the placenta to infect the fetus and EHEC does not
EPEC rearranges host cell actin and EHEC does not

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Microorganisms and Disease
What is common in catheters and ventilators?

They predispose patients to viral rather than bacterial infections
Bacteria responsible for associated infections are usually susceptible to antibiotics
They are used primarily in neonatal intensive care units
They bypass important defenses of the body

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