Microorganisms and Disease
Cholera toxin is an A-B type toxin in which the B portions bind to a receptor on a host cell and the A portion enters the cell to cause

cleavage of rRNA that results in disruption of ribosome function
ADP ribosylation of a G protein that locks it into an active form that stimulates adenylate cyclase to make cAMP
ADP ribosylation of adenylate cyclase that stops production of cAMP
ADP ribosylation of guanylate cyclase that stimulates production of cGMP

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Microorganisms and Disease
What is common in catheters and ventilators?

They are used primarily in neonatal intensive care units
They predispose patients to viral rather than bacterial infections
They bypass important defenses of the body
Bacteria responsible for associated infections are usually susceptible to antibiotics

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Microorganisms and Disease
Which of the following is true regarding anthrax?

Anthrax is caused by a virus
Anthrax is highly contagious
Inhalation Anthrax requires infection with a large number of spores
Inhalation anthrax and cutaneous anthrax are caused by separate strains of Bacillus anthracis

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Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

Diphtheria toxin and edema toxin are ADP ribosylating toxins
The most serious disease symptoms are the direct result of toxin action
Both organisms are gram-positive spore formers
Both organisms cause skin and respiratory tract infections

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