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Monoclonal Antibodies

Monoclonal Antibodies
Which type of cell actually secrets antibodies?

plasma cells
T cells
dendritic cells
macrophages

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Monoclonal Antibodies
In human B cells and T cells are matured in the

lymph nodes and spleen respectively
bursa and thymus respectively
bone marrow and thymus respectively
none of these

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Monoclonal Antibodies
T cells are the source of

lymphotoxin
interferon
all of these
interleukin

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Monoclonal Antibodies
The antigen-specific lymphocytes can be immortalized by which of the following method?

Hybridization with a suitable lymphoid tumor cell
Transformation following infection by Epstein-Barr virus (EB V)
All of these
Transfection with tumor derived DNA

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Monoclonal Antibodies
The Ig locus is about

2/3rd of all hybridomas
l/2nd of all hybridomas
1/4th of all hybridomas
l/3rd of all hybridomas

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Monoclonal Antibodies
The hybrid cells can be propagated

both (a) and (b)
in tissue culture
none of these
as ascites in peritoneal cavity of mice

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