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Monoclonal Antibodies

Monoclonal Antibodies
Which type of cell actually secrets antibodies?

dendritic cells
T cells
plasma cells
macrophages

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Monoclonal Antibodies
The primary B cell receptor is

IgA
IgE
IgD
IgG

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Monoclonal Antibodies
In human B cells and T cells are matured in the

bursa and thymus respectively
none of these
bone marrow and thymus respectively
lymph nodes and spleen respectively

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Monoclonal Antibodies
Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the

All of these
poor recognition of immunoglobulin, Ig constant regions
absence of human immune response against murine proteins (HAMA) response
presence of HAMA response

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Monoclonal Antibodies
The antigen-specific lymphocytes can be immortalized by which of the following method?

Transformation following infection by Epstein-Barr virus (EB V)
Transfection with tumor derived DNA
All of these
Hybridization with a suitable lymphoid tumor cell

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Monoclonal Antibodies
Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with

IgA
Ig MAbs
IgE
IgG

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